NON-INVASIVE DETECTION OF EXOSOMAL MICRORNAS VIA TETHERED CATIONIC LIPOPLEX NANOPARTICLES (TCLN) BIOCHIP FOR LUNG CANCER EARLY DETECTION

Non-invasive Detection of Exosomal MicroRNAs via Tethered Cationic Lipoplex Nanoparticles (tCLN) Biochip for Lung Cancer Early Detection

Circulating microRNAs carried by exosomes have emerged as promising diagnostic biomarkers for cancer because of their abundant amount and remarkable stability pink chiclets gum in body fluids.Exosomal microRNAs in blood are typically quantified using the RNA isolation-qRT-PCR workflow, which cannot distinguish circulating microRNAs secreted by canc

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Biologics as well as inhaled anti-asthmatic therapy achieve clinical remission: Evidence from the Severe Asthma Network in Italy (SANI)

Background: This study aimed to evaluate the impact of severe asthma (SA) treatments after 12 months in achieving clinical remission (CR) within the context of the Severe Asthma Network in Italy (SANI) using the recent SANI definition of CR on treatment.Methods: CR has been defined by SANI as complete, partial, and no CR.Complete CR is defined by t

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Randomized pilot trial for the efficacy of the MMF07 foot massager and heat therapy for restless legs syndrome.

BackgroundRestless Legs Syndrome (RLS) is a sensorimotor condition with a wide range of severity.Symptoms negatively affect sleep and quality of life.Pharmacologic options are not universally 173rd airborne brigade patch effective and side effects are common.Objective data regarding non-pharmacologic treatment is limited.The study objective was to

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Reduced childhood social attention in autism model marmosets predicts impaired social skills and inflexible behavior in adulthood

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social and communication impairments and restricted and repetitive behavior.Although there is currently no established cure for ASD, early interventions for deficits of attention to other individuals are expected to reduce the progression of ASD symptoms in later life

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